Metabolism of cyclic adenosine 3',5'-monophosphate and induction of tryptophanase in Escherichia coli

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Stimulation of tryptophanase synthesis in Escherichia coli by cyclic 3',5'-adenosine monophosphate.

Cyclic 3’,5’-AMP stimulates the rate of tryptophanase synthesis in Escherichia coli treated with tris(hydroxymethyl)aminomethane and ethylenediaminetetraacetic acid and induced with tryptophan. A maximal effect occurs at 4 X low4 M cyclic 3’,5’-AMP and a half-maximal response at 1.5 X lo-4 M. The action of cyclic 3’,5’-AMP is specific for tryptophanase since the over-all rate of protein and RNA...

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Stimulation of Tryptophanase Synthesis in Escherichia coli by Cyclic 3’, S-Adenosine Monophosphate

Cyclic 3’,5’-AMP stimulates the rate of tryptophanase synthesis in Escherichia coli treated with tris(hydroxymethyl)aminomethane and ethylenediaminetetraacetic acid and induced with tryptophan. A maximal effect occurs at 4 X low4 M cyclic 3’,5’-AMP and a half-maximal response at 1.5 X lo-4 M. The action of cyclic 3’,5’-AMP is specific for tryptophanase since the over-all rate of protein and RNA...

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Cyclic adenosine 5'-monophosphate in Escherichia coli.

INTRODUCTION ................ ROLE OF CYCLIC AMP IN REGULATION OF GENE EXPRESSION .......... A Positive Element in Gene Expression ...................................... CRP .......................... :........................................... Direct stimulation of gene expression ...................................... Possible Role As a Negative Element .........................................

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Adenosine 3':5'-cyclic monophosphate control of the enzymes of glutamine metabolism in Escherichia coli.

The effect of cAMP on the intracellular levels of five enzymes concerned with the interconversion of glutamate and glutamine in E. coli has been examined. Cyclic AMP added to the culture medium increases the levels of glutamate dehydrogenase (EC 1.4.1.4) and glutamine synthetase (EC 6.3.1.2); it decreases the levels of glutamate synthase (EC 1.4.1.X), and glutaminase A (EC 3.5.1.2). Cyclic AMP ...

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3',5'-cyclic adenosine monophosphate-requiring mutants of Escherichia coli.

Mutants that require exogenous 3',5'-cyclic adenosine monophosphate (cAMP) for exponential growth were isolated from strains deficient in adenyl cyclase. Studies of one strain showed that cAMP is not incorporated into macromolecules; instead, it seems to have a regulatory function, i.e., in media lacking cAMP, cells form ribonucleic acid (RNA) and protein at linear rather than exponential rates...

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ژورنال

عنوان ژورنال: Journal of Bacteriology

سال: 1975

ISSN: 0021-9193,1098-5530

DOI: 10.1128/jb.124.1.380-390.1975